a 70-year-old Woman Presents to Her Physician with Complaints of Persistent Joint Pain and Stiffness Especially in the Morning, Particularly in Her Hands and Knees. She Describes Difficulty Performing Daily Activities, Such as Buttoning Clothes or Gripping Objects, Due to the Pain. Upon Examination, the Healthcare Provider Notes Swelling, Tenderness and Limited Range of Motion in the Affected Joints. Imaging Studies Reveal Evidence of Joint Erosion and Cartilage Loss